Don't require any more work in-the-moment than you absolutely have to! Spend a boatload of time and effort to set things up beforehand, so that they can just click straight through with no other thought. Or, barring that, have several things already set up, to be able to choose one quickly with just one button each, and have it work.At one point they will go to the computer and quickly type something...At the end of this, they'll be back onstage...The problem is, if they forget...
Live-on-Air and Live-on-Stage are stressful enough already. Keep that workload to an ABSOLUTE minimum! So no typing at all if you can avoid it. Just one button at a time, and that's it. Everything is set up and tested beforehand, even if you don't end up using most of it.
THAT might put you back into OBS, where each button corresponds to a macro. Each macro then, does everything required, already set-up and tested, with no more interaction than just the one trigger hotkey for each.