That happens sometimes, but seems to more often when the GPU or CPU is heavily loaded. Which is going to happen on a modern game with an i7-970+GTX780 combo, if you have the graphical settings turned up.
Also, would strongly advise setting your bitrate to 2000kbps instead of the 3372 it's presently set at, unless you're a Twitch Partner. Your viewers are going to get a lot of buffering at that rate, and I'm not sure where the current number is coming from... guessing a speedtest result of some sort?