Personally,
I had two issues reguarding Windows 10. first, game capture and window capture tend to lower the in-game performance of some games, source games is the best example of this, like l4d2. the capture in-itself works great, its the performance hit when hooking it.
My theory is, Windows 10 has done away with some parts of Aero (not sure exactly what OBS uses inside of Aero), but they removed some of the transparencies and glass that we saw in Windows 7. Aero still shows enabled in OBS regardless\\
Second issues is with the newest build build 10240 where they enabled the xbox app and, in particular game DVR, which enforces desktop vsync (not really an OBS issue) but the game dvr in itself is yet another hook that creates a game overlay for all full screen games. This can be disabled by pressing start then typing xbox, clicking settings on the bottom left (the gear) then the DVR tab, turning of GameDVR at the top.
Other than the above issues, I am able to capture games in windowed mode with monitor capture 720@60 medium preset with almost no game impact.