Dropped frames can only be caused by a failure in your internet connection or your networking hardware. It is not caused by OBS. Follow the troubleshooting steps at:
Dropped Frames and General Connection Issues. The quick fix is to enable Dynamic Bitrate. Settings > Advanced > Network.
You should also consider the following:
1. Audio buffering hit the maximum value. This is an indicator of very high system load, will affect stream latency, and may even cause individual audio sources to stop working. Keep an eye on CPU usage especially, and close background programs if needed. Occasionally, this can be caused by incorrect device timestamps. Restart OBS to reset buffering.
Source affected (potential cause):
Cable D
2.At least one of your audio devices has a sample rate that doesn't match the rest. This can result in audio drift over time or sound distortion. Check your audio devices in Windows settings (both Playback and Recording) and ensure the Default Format (under Advanced) is consistent. 48000 Hz is recommended.
OBS Sample Rate:
48000 Hz
CABLES-A-D Input (VB-Audio Cable D):
48000 Hz
Microphone (NVIDIA Broadcast):
48000 Hz
VoiceMeeter Aux Output (VB-Audio VoiceMeeter AUX VAIO):
44100 Hz
VoiceMeeter VAIO3 Output (VB-Audio VoiceMeeter VAIO3):
44100 Hz
3. Multiple Game Capture sources are usually not needed, and can sometimes interfere with each other (scenes Recording and Vtuber). You can use the same Game Capture for all your games. If you change games often, try out the hotkey mode, which lets you press a key to select your active game. If you play games in fullscreen, use 'Capture any fullscreen application' mode.