Get the low hanging fruit out of the way.
Disable HAGS
SE is nothing but errors. Java Script errors are known to cause issues. You need to fix or remove all of them.
Run a quick test, create a new Profile with just a VLC source. Make sure there are no audio filers in use & no SE. See if things improve.
Just a small sample.
09:13:26.160: [obs-browser: 'Latest static horizontal'] Error: [Report Only] Refused to load the script '
https://streamelements.com/z/i.js' because it violates the following Content Security Policy directive: "script-src 'none'". Note that 'script-src-elem' was not explicitly set, so 'script-src' is used as a fallback.
09:13:26.160: (
https://streamelements.com/overlay/...xnY2fc54WygAaeKKokr6h1RNynakN18NoGS_QjenpUY:0)
09:13:26.166: [obs-browser: 'Latest activity'] Error: [Report Only] Refused to load the script '
https://streamelements.com/z/i.js' because it violates the following Content Security Policy directive: "script-src 'none'". Note that 'script-src-elem' was not explicitly set, so 'script-src' is used as a fallback.
09:13:26.166: (
https://streamelements.com/overlay/...xnY2fc54WygAaeKKokr6h1RNynakN18NoGS_QjenpUY:0)
09:13:26.171: [obs-browser: 'Chat'] Error: [Report Only] Refused to load the script '
https://streamelements.com/z/i.js' because it violates the following Content Security Policy directive: "script-src 'none'". Note that 'script-src-elem' was not explicitly set, so 'script-src' is used as a fallback.
09:13:26.171: (
https://streamelements.com/overlay/...xnY2fc54WygAaeKKokr6h1RNynakN18NoGS_QjenpUY:0)
09:13:26.216: [obs-browser: 'Latest static horizontal'] Error: [Report Only] Refused to load the script '
https://streamelements.com/overlay/scripts/vendor.js' because it violates the following Content Security Policy directive: "script-src 'none'". Note that 'script-src-elem' was not explicitly set, so 'script-src' is used as a fallback.
09:13:26.216: (
https://streamelements.com/overlay/...xnY2fc54WygAaeKKokr6h1RNynakN18NoGS_QjenpUY:0)
09:13:26.284: [obs-browser: 'Latest activity'] Error: [Report Only] Refused to load the script '
https://streamelements.com/overlay/scripts/vendor.js' because it violates the following Content Security Policy directive: "script-src 'none'". Note that 'script-src-elem' was not explicitly set, so 'script-src' is used as a fallback.
09:13:26.284: (
https://streamelements.com/overlay/...xnY2fc54WygAaeKKokr6h1RNynakN18NoGS_QjenpUY:0)
09:13:26.329: [obs-browser: 'Chat'] Error: [Report Only] Refused to load the script '
https://streamelements.com/overlay/scripts/vendor.js' because it violates the following Content Security Policy directive: "script-src 'none'". Note that 'script-src-elem' was not explicitly set, so 'script-src' is used as a fallback.
09:13:26.329: (
https://streamelements.com/overlay/...xnY2fc54WygAaeKKokr6h1RNynakN18NoGS_QjenpUY:0)
09:13:26.531: [obs-browser: 'Chat'] Error: [Report Only] Refused to evaluate a string as JavaScript because 'unsafe-eval' is not an allowed source of script in the following Content Security Policy directive: "script-src 'none'".
09:13:26.531: (
https://streamelements.com/overlay/scripts/vendor.js:47919)
09:13:26.546: [obs-browser: 'Latest static horizontal'] Error: [Report Only] Refused to evaluate a string as JavaScript because 'unsafe-eval' is not an allowed source of script in the following Content Security Policy directive: "script-src 'none'".
09:13:26.546: (
https://streamelements.com/overlay/scripts/vendor.js:47919)
09:13:26.549: [obs-browser: 'Chat'] Error: [Report Only] Refused to load the script '
https://streamelements.com/overlay/scripts/app.js' because it violates the following Content Security Policy directive: "script-src 'none'". Note that 'script-src-elem' was not explicitly set, so 'script-src' is used as a fallback.
09:13:26.549: (
https://streamelements.com/overlay/...xnY2fc54WygAaeKKokr6h1RNynakN18NoGS_QjenpUY:0)
09:13:26.556: [obs-browser: 'Latest static horizontal'] Error: [Report Only] Refused to load the script '
https://streamelements.com/overlay/scripts/app.js' because it violates the following Content Security Policy directive: "script-src 'none'". Note that 'script-src-elem' was not explicitly set, so 'script-src' is used as a fallback.
09:13:26.556: (
https://streamelements.com/overlay/...xnY2fc54WygAaeKKokr6h1RNynakN18NoGS_QjenpUY:0)
09:13:26.679: [obs-browser: 'Latest activity'] Error: [Report Only] Refused to evaluate a string as JavaScript because 'unsafe-eval' is not an allowed source of script in the following Content Security Policy directive: "script-src 'none'".
09:13:26.679: (
https://streamelements.com/overlay/scripts/vendor.js:47919)
09:13:26.689: [obs-browser: 'Latest activity'] Error: [Report Only] Refused to load the script '
https://streamelements.com/overlay/scripts/app.js' because it violates the following Content Security Policy directive: "script-src 'none'". Note that 'script-src-elem' was not explicitly set, so 'script-src' is used as a fallback.
09:13:26.689: (
https://streamelements.com/overlay/...xnY2fc54WygAaeKKokr6h1RNynakN18NoGS_QjenpUY:0)
09:13:26.880: [obs-browser: 'Chat'] Error: [Report Only] Refused to evaluate a string as JavaScript because 'unsafe-eval' is not an allowed source of script in the following Content Security Policy directive: "script-src 'none'".
09:13:26.880: (
https://streamelements.com/overlay/scripts/app.js:397)
09:13:26.880: [obs-browser: 'Chat'] Error: [Report Only] Refused to evaluate a string as JavaScript because 'unsafe-eval' is not an allowed source of script in the following Content Security Policy directive: "script-src 'none'".