Sure you can. The sources within your scene are displayed in order as specified in the Scenes pane. So when you have your camera above an Image source (or video playing or ie. a window capture of a PowerPoint presentation) it will be shown on top of it.
You might need to separate the person(s) who are appearing at camera from their background. Therefor you will need a green screen and a chroma key filter at the camera source.
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