I'd recommend Starting by uninstalling that PoS streamelements plugin, which pukes all over the logs and is a too-frequent common coincidence with problem systems
You have audio sources at different sampling rates - fix that
You may want to look into the StreamFX plugin with with AMD GPU encoder offload support
18:23:17.118: Output 'simple_stream': Number of lagged frames due to rendering lag/stalls: 89 (11.8%)
then your log is full of network issue from name lookup, connection, and throughput
18:23:17.118: Output 'simple_stream': Number of dropped frames due to insufficient bandwidth/connection stalls: 520 (77.6%)
are you the only one using the Internet connection, or do you have a house full of folks also video conferencing and other upload traffic consumers?