Your're overloading your system. Start with standard recording with 1920x1080 at 60 fps in simple output mode, encoder nvenc and quality "indistinguishable quality". Record to a local disk, no USB drive or network drive.
Increase and change settings one by one, and at each step make a test recording to make sure your recording is still without choppiness. This way you find out which of the questionable options of yours are the culprit.
Major points:
- don't record 4k lossless
- don't record to a remote drive. lossless 4k must probably go to a highspeed SSD.
- don't record higher fps before you make sure 60 fps works
- use color space partial, not full