Please provide more info/context. What issue?
Do you have varying video lag across the 3 cameras? all NDI, right? Assuming NDI, are the cameras running the same NDI version?
Have you used the PTZoptics posted audio/video sync video (the short video clip, run on a laptop/tablet etc and use to get a sense of audio delay required to get into sync?
real-time video encoding is VERY computationally demanding.
Are you monitoring hardware resource (CPU, GPU, RAM, etc) utilization [for ex. using Task manager’s Performance tab and/or Resource Monitor] to see if your system is being maxed out with your settings?