audio De-Verb / DSP

In the mixer, find the audio source you want to add Noise Suppression to, press the cog wheel next to the fader, and choose "Filters". From there, press the + button and add Noise Suppression, and adjust as desired.
 
Maybe route your audio through an external program (DAW, something built to handle complex audio issues), and feed that into OBS.

Or fix your environment/gear so your audio sounds good coming into the system.
 
Noise is a problem best solved at the source. Wear a headset with a boom mounted microphone. That will solve most of your ambient noise issues.
 
Hi! It's 2021 and NVIDIA has 2 modes for it's AI - powered noise removal algo. The original noise suppression algo can be selected within OBS noise suppression filter, after installing the NV SDK for it. Hopefully, the room echo will be added/embedded into OBS soon, too!
 
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