What's your usage with it looking like? I actually use that exact virtual audio cable myself. My set up is using pluginhost2 to have my audio interface operate in ASIO mode and bypass most of OBS's audio system. This relies on VAC to handle the devices necessary to accomplish the routing though. My Audio interface is a Motu M2.
I have no idea if I've set things up in a standard fashion or not, I'm entirely self-taught on audio stuff. Essentially the goal here is to use ASIO, have every audio source separated so I can have different streaming locations receiving different audio as well as having everything on tracks for a recording so I can get rid of things like a friend on discord being loud in a moment I wanted a clip of, etc.
The other thing I use this for is to feed my processed mic back into a VAC so other programs can receive that instead of only OBS having the nice mic.
If there's anything you want me to test or confirm for you as far as VAC settings go, let me know!
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VAC v4.71