You can do it, but likely will get subtle judder due to frame pacing. If you can run at 120hz it will be less noticeable, as OBS could then just take every other frame. With 75hz, it has to take a few, skip one, take a few more... and there's no guarantee that this 'hitch' will happen after the same number of frames each time (though in this case it would take 4 frames, then skip 1).
The only way to avoid this is to either play at a full integer multiplier of your final framerate, or to use interpolation smoothing, which OBS does not perform. But you COULD record at 75fps and then convert down in your video editor. It likely will come with a quality loss though, as frame interpolation isn't magic, just computed guessing at what the frame should look like.
Really though, just play at 60fps.