1. Record to MKV
2. The encoder is skipping frames because of CPU overload. Read
https://obsproject.com/wiki/General-Performance-and-Encoding-Issues
3. Run OBS as Admin
4. Your GPU is maxed out and OBS can't render scenes fast enough. Running a game without vertical sync or a frame rate limiter will frequently cause performance issues with OBS because your GPU will be maxed out. OBS requires a little GPU to render your scene.
Enable Vsync or set a reasonable frame rate limit that your GPU can handle without hitting 100% usage.
If that's not enough you may also need to turn down some of the video quality options in the game. If you are experiencing issues in general while using OBS, your GPU may be overloaded for the settings you are trying to use.
See
https://obsproject.com/wiki/GPU-overload-issues
5. Display and Game Capture Sources interfere with each other. Never put them in the same scene.
6. Multiple Game Capture sources are usually not needed, and can sometimes interfere with each other. You can use the same Game Capture for all your games! If you change games often, try out the hotkey mode, which lets you press a key to select your active game. If you play games in fullscreen, use 'Capture any fullscreen application' mode.
If still having issues after making those changes, use the
Log Analyzer or post new log.