The logs are showing your Presonus AudioBox had problems getting initialized. Something unstable is happening that you need to resolve.
OBS couldn't find AudioBox in the Windows registry. Did you uninstall? Move the software to another location? Run something like CCleaner, Glary or similar that does registry validation and removes it if no association?
Maybe try removing and install AudioBox software again. A new version of Universal Control came out two days ago:
www.presonus.com
02:52:45.460: [WASAPISource::TryInitialize]:[Lautsprecher (AudioBox USB iOne)] Failed to activate client context: 88890004
02:52:45.460: [WASAPISource::WASAPISource] Device '{0.0.0.00000000}.{955cc1f3-d53e-4e8c-bbae-1044a66ade83}' not found. Waiting for device
02:52:45.461: [WASAPISource::TryInitialize]:[Line (AudioBox USB iOne)] Failed to activate client context: 88890004
02:52:45.461: [WASAPISource::WASAPISource] Device '{0.0.1.00000000}.{825a0952-fce1-40ea-988d-482097d51394}' not found. Waiting for device
02:52:45.463: [WASAPISource::TryInitialize]:[Line (AudioBox USB iOne)] Failed to activate client context: 88890004
02:52:45.463: [WASAPISource::WASAPISource] Device '{0.0.1.00000000}.{825a0952-fce1-40ea-988d-482097d51394}' not found. Waiting for device