The ones I am using that seem to have an impact are:
1. Delay
2. Reverb
3. Speech Volume Leveler
4. Adaptive Noise Reduction
Obviously I don't NEED this, just been playing around and like the sound. If I remove Delay and Reverb the delay drops to about 750ms which I can compensate for, but I would love it if I could get it all working. If I change from Speech Volume Leveler to Amplify there is very little lag, but I don't get the nice even audio that Speech Volume Leveler gives me.
I don't have a proper soundcard. I am running a Rode Podcaster over USB into the computer, then using that as the input in Audition with Virtual Audio Cable Line 1 as the output. When I enable the preset I have created Audition warns me that effects I have enabled can cause delay and CPU usage. I'm running an i7-6900k, and the program doesn't show much CPU usage really.
I am brand new to Audition, only use Audacity in the past, so it is obviously 100% possible that I have done something incorrectly to cause this large of a delay, but I'm not sure what.