Question / Help Gain: Mixing Board/Mic Vs. OBS

Was curious to know....should one increase / set the Gain on a Mixing Board / Mic or in OBS when it comes to setting up audio Levels? How do you guys set up yours? From what I've read, it seems to be split 50/50. Some say never increase on a Mic and to do it in OBS, and others, just the opposite. Thanks.
 
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