As far as I know none of those things matter. Whatever your target FPS is, having studio mode on reduces it because of the way the dual preview window is drawn. It doesn't affect the multiview window, so the only workaround I'm aware of is this:
Turn on windowed multiview.
Turn on the Stats window.
Set hotkeys for your scenes and the Transition button.
Turn on studio mode.
Minimize the main OBS window.
Select Finder or some other application as front-most.
You should now be able to select scenes and transition them while viewing the results in the Multiview window with a greatly minimized hit to framerate (but not NO impact).
For instance I just did a test and with the main window showing the studio mode previews, FPS dropped from 30 to 16.
With the above workaround, the framerate hovers between 26 and 30.