Add your source to your scene.
Add the same source again to the scene using "Add Existing". Add each source to it's own group. I called them "Fore" and "Back".
To the lower group in the list, add a Color Correction filter and set the saturation to -1.
To the upper group add a Chroma Key filter, change the Key Color Type to Custom, and select the color you want to desaturate. The "Similarity" slider spreads the range of the hue you selected. I added a Color Correction filter to increase the saturation for a little added "pop".
Here's the final result.