First off:
I am not bashing OBS, but using the OBS gamecapture (if you have crossfire) is really not something you want to do. It kills performance imo. Luckily, there is a better way without sacrificing performance and still using OBS.
Actually you have two other options and they will give your darn near a zero performance hit.
Option#1-preferred method
Use Dxtory to cap the footage using RawCap and DirectShow Ouptut.
Add a video camera device in OBS with the Dxtory directshow output (Dxtory Video 1) as the device.
voila, crossfire full screen game capture for streaming with relatively zero performance hit. Yes it works flawlessly and I honestly see no difference in performance doing it this way whether I am streaming or not (so it is effectively a zero hit for me). Your experience may differ, but I doubt it.
here are the settings:
dxtory:
OBS:
Option#2 (only posted this option to show some other program managed it once, so it is possible)
There has only been one other method of streaming or capturing crossfire with relatively zero performance hit and that was using an older version of Action!.
In version 1.17.3 Action! was using AMD APP (NOT VCE!) and you could stream to twitch without losing any FPS. Then they went to version 1.20.2 and broke it and it hasn't worked since lol. But if you stilll had a old version of that, you could use it. The problem is, Action! is very limited to basic functionality for streaming. Really not sure why other programs have not tried the APP route versus VCE. I am not a program guy, so I am just asking. I know APP is older, but it sure does seem to work miles better to me.
I have videos showing just about every single streaming/capture program using crossfire. Trust me, the only two that really work without crushing performance are the two I just mentioned. Personally, I'd just use dxtory into OBS, it works fine and the only downside is that it costs like $34 for dxtory.
Here I am streaming @720P/30 fps while playing at 3200X1800 in BF4 with all settings on ultra and still getting over 100 FPS. You cannot do that with OBS's gamecapture, but here it is with OBS and Dxtory together:
http://www.twitch.tv/the9quad/c/5726630
here is 1440p all ultra streaming at 720p/30fps (this was Action! 1.17.3)
http://www.twitch.tv/the9quad/c/5424984
so yes it is possible to capture footage or stream it in crossfire with little to no performance penalty, and with out any weird graphical anomalies. Unfortunately, it takes two programs to do it or one old limited in functionality program.
System that was tested on was a i7 4930k @4.4 ghz, Three R9-290x's, 32 gigs of DDR3 @2400mhz, and windows 8.1 for reference.
I have tested:
OBS, X-Split. Playclaw, Action!, Dxtory, Overwolf, Raptr, FFSplit( wont do full screen-so useless),D3Dgear, and wirecast, but none worked very well except the two methods above.