@soulie Yes, it's possible, here is download link
Did you know that you can put all audio in one scene and then add it to scenes via nested scene ?
Fix audio filters creation in microphone sources
Changed hotkey registering logic. You also might want to check obs-libre-macros - Scripting and macros hotkeys in OBS Studio for Humans
Added hold feature so when you hold hotkey (pressed down for some period of time) filter is active, otherwise it's inactive.
download here : https://github.com/upgradeQ/obs-filter-hotkeys/releases/tag/0.2.0